Pathologic Changes of the Peripheral Vestibular System Secondary to Chronic Otitis Media.
نویسندگان
چکیده
OBJECTIVE To evaluate the histopathologic changes of dark, transitional, and hair cells of the vestibular system in human temporal bones from patients with chronic otitis media. STUDY DESIGN Comparative human temporal bone study. SETTING Otopathology laboratory. SUBJECTS AND METHODS To compare the density of vestibular dark, transitional, and hair cells in temporal bones with and without chronic otitis media, we used differential interference contrast microscopy. RESULTS In the chronic otitis media group (as compared with the age-matched control group), the density of type I and type II hair cells was significantly decreased in the lateral semicircular canal, saccule, and utricle (P < .05). The density of type I cells was also significantly decreased in the chronic otitis media group in the posterior semicircular canal (P = .005), but that of type II cells was not (P = .168). The mean number of dark cells was significantly decreased in the chronic otitis media group in the lateral semicircular canal (P = .014) and in the posterior semicircular canal (P = .002). We observed no statistically significant difference in the density of transitional cells between the 2 groups (P > .1). CONCLUSION The findings of our study suggest that the decrease in the number of vestibular sensory cells and dark cells could be the cause of the clinical symptoms of imbalance of some patients with chronic otitis media.
منابع مشابه
Labyrinthine Fistulae in Squamosal Type of Chronic Otitis Media: Therapeutic Outcome
Introduction: Labyrinthine fistulae (LF) are the common complications of chronic otitis media (COM) of squamosal variety. The final therapeutic outcome of this condition is to preserve the cochlear and vestibular functions. Herein, we present the data of the cases managed at our institute with respect to their presenting complaints, adopted therapeutic approaches and outcomes. <br ...
متن کاملTHE. ROUND WINDOW NICHE AND MEMBRANE IN CHRONIC SUPPURATIVE OTITIS MEDIA
This study evaluated the histopathologic changes in the round window niche. , and membrane in cases of chronic suppurative otitis media. The pathologic process was found in all subjects. Fibrocystic or fibrous tissue was most commonly seen, while active granulation was less developed. The round window membrane was thicker and inflamed throughout its layers. Inflammatory invasion of the inne...
متن کاملResults of Air Caloric and Other Vestibular Tests in Patients with Chronic Otitis Media
OBJECTIVES Air caloric results are supposed to be influenced by anatomic changes of the middle ear. The aims of our study were to evaluate the incidence and characteristics of abnormal air caloric results in patients with unilateral chronic otitis media and without any history of vertigo, and to compare caloric results with there of other vestibular function tests (VFTs). METHODS Twenty five ...
متن کاملAssociation Between Audiometric Profile and Intraoperative Findings in Patients with Chronic Suppurative Otitis Media
Introduction: Although the incidence and prevalence of chronic suppurative otitis media (CSOM) has been decreased in recent decades, but it is still a major health problem in both developing and developed countries. CSOM can cause major and life-threatening complications such as hearing loss, meningitis and cerebral abscess. Since hearing loss is the most common complication of CSOM, we aimed ...
متن کاملTuberculous Otitis Media Leading to Sequentialib Bilateral Facial Nerve Paralysis
Introduction: Tuberculous otitis media (TOM) is an uncommon, insidious, and frequently misdiagnosed form of tuberculosis (TB). In particular, TOM is usually secondary to direct transmission from adjacent organs, while the primary form has been rarely reported. The main aim of treatment is to start the patient on an antitubercular regime and early surgical intervention to decompress the facial n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
دوره 155 3 شماره
صفحات -
تاریخ انتشار 2016